Jessica Spencer, MD, MSc

Associate Professor

Department of Gynecology and Obstetrics, Reproductive Endocrinology and Infertility

Division Director

Reproductive Endocrinology and Infertility

Fellowship Director

Reproductive Endocrinology and Infertility

Office: Emory Reproductive Center, Emory University Hospital Midtown, Medical Office Tower, 18th Floor

Phone: 404-778-3401

Biography

Education and Training

Medical Education: Sackler School of Medicine, MD, 2001 
Residency: 
•  Tufts University/New England Medical Center, Department of Obstetrics and Gynecology, 2003
•  David Geffen School of Medicine at U.C.L.A., Department of Obstetrics and Gynecology, 2005 
Fellowship: Emory University School of Medicine, Division of Reproductive Endocrinology and Infertility, 2008
Graduate Education: The Rollins School of Public Health at Emory University, MSc, 2007


Certifications

•  American Board of Obstetrics and Gynecology, Obstetrics and Gynecology, 2007
•  American Board of Obstetrics and Gynecology, Reproductive Endocrinology and Infertility, 2011


Areas of Interest

•  Premature ovarian insufficiency
•  Infertility - in vitro fertiiization, preimplantation genetic diagnosis
•  Fertility preservation 
•  Investigating the mechanisms of premature ovarian insufficiency in women with galactosemia and Fragile X permutation
•  Reproductive outcomes in cancer survivors


Awards and Honors

•  Atlanta Magazine Top Doctor, 2016
•  Excellence in Teaching Award, Reproductive Sciences, Emory, 2010, 2012, 2013, 2014
•  Outstanding Speaker Award, AACC conference, 2012
•  Millipub Club, Emory, 2012
•  Golden Apple Teaching Award, Emory, 2009


Society and Professional Memberships

•  American College of Obstetricians & Gynecologists
•  American Society for Reproductive Medicine
•  Society of Reproductive Endocrinology and Infertility
•  Endocrine Society
•  Georgia Obstetrical and Gynecological Society
•  Atlanta Obstetrical and Gynecological Society

Research

Articles

Hartnett KP, Ward KC, Kramer MR, Lash TL, Mertens AC, Spencer JB, Fothergill A, Howards PP. The risk of preterm birth and growth restriction in pregnancy after cancer. Int J Cancer. 2017 Aug 24. doi: 10.1002/ijc.30914. [Epub ahead of print] PMID: 28836277


Travers CD, Spencer JB, Cwiak CA, Mertens AC, Howards PP. Urban-Rural Differences in Tubal Ligation Incidence in the State of Georgia, USA. J Rural Health. 2017 Jul 21. doi: 10.1111/jrh.12259. [Epub ahead of print] PMID: 28731204


Jacobson MH, Chin HB, Mertens AC, Spencer JB, Fothergill A, Howards PP. “Research on Infertility: Definition Makes a Difference” Revisited. Am J Epidemiol. 2017 Jun 14. doi: 10.1093/aje/kwx240. [Epub ahead of print] PMID: 28633422


Cottrell HN, Wu J, Rimawi BH, Duran JM, Spencer JB, Sidell N, Rajakumar A. Human endometrial stromal cell plasticity: Reversible sFlt1 expression negatively coincides with decidualization. Hypertens Pregnancy. 2017 May 11:1-8. doi: 10.1080/10641955.2017.1299172. [Epub ahead of print] PMID: 28494174


Shandley LM, Spencer JB, Fothergill A, Mertens AC, Manatunga A, Paplomata E, Howards PP. Impact of tamoxifen therapy on fertility in breast cancer survivors. Fertil Steril. 2017 Jan; 107(1):243-252.e5. doi: 10.1016/j.fertnstert.2016.10.020. Epub 2016 Nov 22. PMID: 27887709


Chin HB, Howards PP, Kramer MR, Mertens AC, Spencer JB. Which female cancer patients fail to receive fertility counseling before treatment in the state of Georgia? Fertil Steril. 2016 Dec;106(7):1763-1771.e1. doi: 10.1016.fertnstert.2016.08.034. Epub 2016 Sep 24. PMID: 27678034


Welling L, Bernstein LE, Berry GT, Burlina AB, Eyskens F, Gautschi M, Grünewald S, Gubbels CS, Knerr I, Labrune P, van der Lee JH, MacDonald A, Murphy E, Portnoi PA, Õunap K, Potter NL, Rubio-Gozalbo ME, Spencer JB, Timmers I, Treacy EP, Van Calcar SC, Waisbren SE, Bosch AM; Galactosemia Network (GalNet). International clinical guideline for the management of classical galactosemia: diagnosis, treatment, and follow-up. J Inherit Metab Dis. 2016 Nov 17. [Epub ahead of print] PMID: 27858262


Knight JH, Howards PP, Spencer JB, Tsagaris KC, Lim SS. Characteristics related to early secondary amenorrhea and pregnancy among women diagnoses with systemic lupus erythematosus: an analysis using the GOAL study. Lupus Sci Med. 2016 Sep 22;3(1):e000139. PMID: 27752355


Hipp HS, Charen KH, Spencer JB, Allen EG, Sherman SL. Reproductive and gynecologic care of women with fragile X primary ovarian insufficiency (FXPOI). Menopause. 2016 Sep;23(9):993-999. PMID: 27552334


Jacobson MH, Mertens AC, Spencer JB, Manatunga AK, Howards PP. Menses resumption after cancer treatment-induced amenorrhea occurs early or not at all. Fertil Steril. 2016 Mar;105(3):765-72.e4. doi: 10.1016/j.fertnstert.2015.11.020. Epub 2015 Dec 1. PMID: 26658130


Chin HB, Kramer MR, Mertens AC, Spencer JB, Howards PP. Differences in Women’s Use of Medical Help for Becoming Pregnant by the Level of Urbanization of County of Residence in Georgia. J Rural Health. 2016 Jan 14. doi: 10.111/jrh.12172. [Epub ahead of print] PMID: 26769080


Chin HB, Jacobson MH, Interrante JD, Mertens AC, Spencer JB, Howards PP. Hypothyroidism after cancer and the ability to meet reproductive goals among a cohort of young adult female cancer survivors. Fertil Steril. 2016 Jan;105(1):202-7. e1-2. doi: 10.1016/j.fertnstert.2015.09.031. Epub 2015 Oct. 30. PMID: 26474733


Chin HB, Howards PP, Kramer MR, Mertens AC, Spencer JB. Racial Disparities in Seeking Care for Help Getting Pregnant. Paediatr Perinat Epidemiol. 2015 Jul 22. doi: 10.1111/ppe.12210 [Epub ahead of print] PMID: 26201443


Elchuri SV, Williamson RS, Clark Brown R, Haight AE, Spencer JB, Buchanan I, Hassen-Schilling L, Brown MR, Mertens AC, Meacham LR. The effects of hydroxyurea and bone marrow transplant on Anti-Müllerian hormone (AMH) levels in females with sickle cell anemia. Blood Cells Mol Dis. 2015 Jun;55(1);56-61. Doi:10.1016/j.bcmd.2015.03.012. Epub 2015 Mar 31. PMID: 25976468


Roberts-Wilson TK, Spencer JB, Fantz CR.  Using an algorithmic approach to secondary amenorrhea: avoiding diagnostic error. Clinica Chimica Acta.2013 Aug 23;423:56-61.


Spencer JB, Badik JR, Ryan EL, Gleason TJ, Broadaway KA, Epstein MP, Fridovich-Keil JL, Modifiers of ovarian function in girls and women with classic galactosemia. Journal of Clinical Endocrinology and Metabolism, 2013 Jul;98(7):E1257-65


Badik J, Castañeda U, Gleason TJ, Spencer JB, Ficicioglu C, Fitzgerald K, Fridovich-Keil JL. Anti-Mϋllerian Hormone Levels in Pre-Pubertal Girls with Duarte Variant Galactosemia Demonstrate No Evidence of Premature Ovarian Insufficiency. Fertility and Sterility, 2011 Epub June 28.


Willis M, Session DR, Spencer JB. Controlled Ovarian Hyperstimulation. Minerva Ginecologica, 2011 Apr;63(2):119-35.


Fridovich-Keil JL, Gubbels CS, Spencer JB, Sanders RD, Land JA, and Rubio-Gozalbo ME. Ovarian function in girls and women with GALT-deficiency galactosemia. Journal of Inherited Metabolic Disease, 2011 Apr;34(2):357-66.


Spencer JB, Browne AS, Copland SD, Session DR. Discontinuation of rLH two days before hCG increases the number of oocytes retrieved in IVF. Reproductive Biology & Endocrinology, 2010; Mar 23;8:29.


Fridovich-Keil JL, Sanders RD, Spencer JB, Epstein MP, Lustbader JW, Vardhana PA. Measures of ovarian function in galactosemia. Fertility and Sterility. 2009 Aug;92(2):e30; author reply e31.


Sanders R*, Spencer J*, Vardhana P, Pollak S, Lustbader J, Fridovich-Keil J. Biomarkers of gonadal reserve in children and adults with classic galactosemia. Fertility and Sterility 2009 Jul;92(1):344-51 *co-first author.


Spencer J, Klein M, Kumar A, Azziz R. The age-associated decline of androgens in reproductive aged and menopausal Black and White women. Journal of Clinical Endocrinology and Metabolism 2007; 92(12):4730-3.


Kusumi K, Sun ES, Kerrebrock AW, Bronson RT, Chi DC, Bulotsky MS, Spencer JB, Birren BW, Frankel WN, Lander ES. The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries. Nature Genetics 1998; 19(3):274-8.


Wang DG, Fan JB, Siao CJ, Berno A, Young P, Sapolsky R, Ghandour G, Perkins N, Winchester E, Spencer J, Kruglyak L, Stein L, Hsie L, Topaloglou T, Hubbell E, Robinson E, Mittmann M, Morris MS, Shen N, Kilburn D, Rioux J, Nusbaum C, Rozen S, Hudson TJ, Lipshutz R, Chee M, Lander ES. Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science 1998; 280(5366):1077-82.


Book Chapters

Berga S, Spencer J. 2009 “Premenstrual Syndrome”, ACP Medicine, New York, NY, Web MD.


Spencer J. “Diabetes Mellitus and Thyroid Disorders” and “Disorders of Reproductive Physiology and Gynecologic Endocrinology”. In: Roberts CP, Broomfield DP, eds. Avoiding Common Obstetrics and Gynecology Errors. Philadelphia PA: Lippincott Williams & Wilkins; 2010:1-2.


DeCherney A, Spencer J, Chard T, Hutchinson K. 2007, ‘Endocrinology of Pregnancy and the Placenta’ in Clinical Obstetrics: The Fetus and the Mother, 3rd ed. ed. by E. Albert Reece and John C. Hobbins. Blackwell Publishing Ltd., USA.


Spencer, J. 2006, ‘Physiology of Pregnancy’ in First Aid for the Obstetrics and Gynecology Boards. ed. Jeannine Rahimian and Tao Le. McGraw-Hill Medical, USA.


Abstracts

Chin HB, Knight JH, Hartnett KP, Kim KH, Spencer JB, Howards PP.  Characterizing the use of fertility preservation methods among female cancer survivors: The FUCHSIA Women’s Study.  Abstract at the Society for Pediatric and Perinatal Epidemiologic Research annual meeting, Boston, MA, 2013


Knight JH, Chin HB, Kim KH, Hartnett KP, Spencer JB, Howards PP.  Comparing fertility treatment success between young adult cancer survivors and women who have not had cancer: The FUCHSIA Women’s Study.  Abstract at the Society for Pediatric and Perinatal Epidemiologic Research annual meeting, Boston, MA, 2013


Kim KH, Hartnett KP, Chin HB, Knight JH, Woodard JJ, Spencer JB, Howards PP.  Understanding young adult cancer survivors' knowledge about fertility preservation and their reasons for not pursuing it in the FUCHSIA Women’s Study.  Abstract at the Society for Pediatric and Perinatal Epidemiologic Research annual meeting, Boston, MA, 2013


Howards PP, Mink PJ, Kim KH, Chin HB, Woodard JJ, Spencer JB, Mertens AC. Fertility in female survivors of young adult cancers:  The FUCHSIA Women’s Study.  Abstract at the Society for Pediatric and Perinatal Epidemiologic Research annual meeting, Boston, MA, 2013


Hartnett KP*, Kim KH, Chin HB, Knight JH, Spencer JB, Howards PP. Are young women with cancer getting enough information about the possible effects of treatment on their future fertility? An analysis from the FUCHSIA Women’s Study.  Abstract at the Society for Pediatric and Perinatal Epidemiologic Research annual meeting, Boston, MA, 2013


Howards PP, Hartnett KP, Mertens AC, Spencer JB.  What determines whether women diagnosed with cancer talk with a doctor about the possible effects of treatment on their fertility: an analysis from The FUCHSIA Women’s Study.  Abstract at the American Society of Reproductive Medicine, Boston, MA 2013


J. Badik, T. Gleason, J. Spencer, J. Fridovich-Keil. Predicted Residual GALT Activity Correlates with Detectable AMH levels in Girls with Classic Galactosemia. Pediatric Academic Societies Annual Meeting, Boston, MA, 2012.


J. Badik, U. Castañeda, T. Gleason, J. Spencer, C. Ficicioglu, K. Fitzgerald, and J. Fridovich-Keil. Anti-Mullerian Hormone Levels in Pre-Pubertal Girls with Duarte Variant Galactosemia Show No Evidence of Premature Ovarian Insufficiency. The Endocrine Society's 93rd Annual Meeting & Expo, Boston, MA, 2011.


J. Spencer, W. Shang, W. Sun, D. Session, D. Ledbetter, C. Lese Martin. Developing a Single Cell Oligonucleotide Array-CGH Test for Aneuploid Screening. Presented at the 63rd annual meeting of the American Society of Reproductive Medicine, Washington DC, 2007.


J. Spencer, E. Wallace, A. Kogan, D. Session, D. Ledbetter, C. Lese-Martin. Oligonucleotide Array Based Comparative Genomic Hybridization with Limited Amounts of DNA Using Whole Genome Amplification. Presented at the 54th annual meeting of the Society for Gynecology Investigation, Reno, 2007.


J. Spencer, D. Kahn, H. Bernstein. Specific Lymphocyte Activation in the Preeclamptic Neonate. Presented at the 52nd annual meeting of the Society for Gynecologic Investigation, Los Angeles, 2005.