Marie Shockley, MD

Assistant Professor

Department of Gynecology and Obstetrics, Gynecologic Specialties

Biography

Education & Training

Medical Education: University of Maryland School of Medicine, MD, 2011
Residency: Eastern Virginia Medical School, Obstetrics and Gynecology, 2015
Fellowship: Cleveland Clinic, Minimally Invasive Gynecologic Surgery, 2017

Awards and Honors

•   Jerome J. Hoffman Award, Best Abstract by a Resident or Fellow, American Association of Gynecologic Laparoscopists, 2016 

•   AAGL Clinical Research Seminar grant from The Foundation of Excellence in Women’s Healthcare, 2016

•   Award, Best Resident Research Presentation, Eastern Virginia Medical School, 2013

•   Alfred Z. Abuhamad OB/Gyn Resident Research Award, Eastern Virginia Medical School, Department of Obstetrics & Gynecology, 2012

•   Recipient of The Baltimore Albert Schweitzer Fellowship for community service, 2008-2009

Society and Professional Memberships

•   AAGL
•   American College of Obstetricians and Gynecologists
•   Gold Humanism Honor Society, University of Maryland School of Medicine
•   American Medical Association

Research

Publications

Beran B, Arnolds K, Shockley M, Rivas K, Medina III M, Escobar PF, Tzakis A, Falcone T, Sprague ML, Zimberg S. Livebirth and utero-placental insufficiency in Papio hamadryas baboons with uterus angiosome perfused by bilateral utero-ovarian microsurgical anastomoses alone. Human Reprod. DOI: 10.1093/humrep/dex242

Shockley ME, Beran B, Nutting H, Arnolds K, Sprague ML, Zimberg S. The Sterility of Selected Operative Sites During Total Laparoscopic Hysterectomy. J Min Invasive Gynecol. DOI: 10.1016/j.jmig.2017.06.004

Shockley M, Arnolds K, Beran B, Rivas K, Escobar P, Tzakis A, Falcone T, Sprague ML, Zimberg S.  Uterine viability in the baboon after ligation of uterine vasculature: a pilot study to assess alternative perfusion and venous return for uterine transplantation.Fertil Steril. 2017 Apr;107(4):1078-1082.

Shockley ME, Salcedo G, Salgueiro JM, Zimberg S, Escobar PF. Seeding by Benign Disease: Mature Cystic Teratoma Recurs at Laparoscopic Port Site. J Min Invasive Gynecol. DOI: 10.1016/j.jmig.2017.01.014.

Beran B, Shockley M, Arnolds K, Escobar P, Zimberg S, Sprague ML. Laser angiography with indocyanine green to assess vaginal cuff perfusion during total laparoscopic hysterectomy: A pilot study. J Min Invasive Gynecol. 2017; 24 (3): 432-437.

Divi RL, Doerge DR, Twaddle NC, Shockley ME, St Claire MC, Harbaugh JW, Harbaugh SW, and Poirier MC.: Metabolism and pharmacokinetics of the combination Zidovudine plus Lamivudine in the adult Erythrocebus patas monkey determined by liquid chromatography-tandem mass spectrometric analysis. Toxicol Appl Pharmacol. 2008 Jan 15;226(2):206-11.

Divi RL, Einem TL, Leonard Fletcher SL, Shockley ME, Kuo MM, St Claire MC, Cook A, Nagashima K, Harbaugh SW, Harbaugh JW, Moirier MC.: Progressive Mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs). Toxicological Sciences. 2010 Nov 118(1): 191-201.

Divi RL, Leonard SL, Walker BL, Kuo MM, Shockley ME, St Claire MC, Nagashima K, Harbaugh SW, Harbaugh JW, and Poirier MC.: Erythrocebus patas monkey offspring exposed perinatally to NRTIs sustain skeletal muscle mitochondrial compromise at birth and at 1 year of age. Toxicol Sci. 2007 Sep;99(1):203-13.

Divi RL, Haverkos KJ, Humsi JA, Shockley ME, Thamire C, Nagashima K, Olivero OA, and Poirier MC.: Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long-term to Zidovudine. Environ Mol Mutagen. 2007 Apr-May;48(3-4):179-89.

John K, Divi RL, Keshava C, Orozco CC, Shockley ME, Richardson DL, Poirier MC, Nath J, and Weston A.: CYP1A1 and CYP1B1 gene expression and DNA adduct formation in normal human mammary epithelial cells exposed to benzo[a]pyrene in the absence and presence of chlorophyllin. Cancer Letters. 2010 Jun 28;292 (2): 254-260.

Divi RL, Lindeman TL, Shockley ME, Keshava C, Weston A, Poirier MC.: Correlation between CYP1A1 transcript, protein level, enzyme activity and DNA adduct formation in normal human mammary epithelial cell strains exposed to benzo[a]pyrene.Mutagenesis. 2014 Nov;29(6):409-17

Poster and Oral Presentations

Shockley M, Beran B, Arnolds, K, Sprague M, Zimberg S: The Sterility of Selected Operative Sites During Total Laparoscopic Hysterectomy. American Association of Gynecologic Laparoscopists Global Congress, Orlando, FL, November 2016.

Shockley M, Beran B, Arnolds, K, Sprague M, Rivas, K, Tzakis A, Zimberg S: Uterine Viability in the baboon following interruption of the uterine arteries and veins bilaterally. American Society for Reproductive Medicine, Salt Lake City, UT, October 2016.

Divi RL, Einem TL, Shockley ME, Keshava C, Weston A, and Poirier MC: Correlation between CYP1A1 RNA transcript, protein level, enzyme activity, and DNA adducts in primary normal human mammary epithelial cells exposed to Benzo[a]pyrene. Environmental Mutagenesis and Genomics Society (EMGS), Orlando, FL, September 2014.

Shockley ME, Divi RL, Keshava C and Poirier MC.: Variations in gene expression copy numbers and enzyme activities of Cytochrome P450 1B1 (CYP1B1) and NAD(P)H:quinone oxidoreductase (NQO1) determine the level of Benzo(a)pyrene-DNA Adduct Formation in Human Mammary Epithelial Cells. American Association of Cancer Research (AACR), Atlanta, GA, October 2007.

Shockley ME, Divi RL, Keshava C and Poirier MC: The role of Cytochrome p450 1B1 and NAD(P)H: quinone oxidoreductase in Benzo(a)pyrene-DNA adduct formation in mammary epithelial cells. NIH Postbacc Research Festival, Bethesda, MD, May 2007.

Shockley ME, Divi RL, Keshava C and Poirier MC: The role of Cytochrome p450 1B1 and NAD(P)H: quinone oxidoreductase in Benzo(a)pyrene-DNA adduct formation in mammary epithelial cells. Annual  Fellows and Young Investigator’s Retreat, sponsored by the Center for Cancer Research, Ocean City, MD, February 2007.

Divi RL, Shockley ME, Leonard SL, Kuo MM, Walker BL, St. Claire MC, Nagashima K, Walker VE, and Poirier MC.: Mitochondrial disease associated with anti-retroviral therapy: Evidence from in vitro and in vivo studies.  “Indo-US Workshop on Mitochondrial Research and Medicine,” Centre for Cellular and Molecular Biology, Hyderabad, India, January 2007.

Shockley ME, Divi RL, John K, Orozco CC, Nath J, Weston A, and Poirier MC: Role of Cytochrome P450 1B1 in Benzo(a)pyrene metabolism, DNA damage and protection by chlorophyllin in human breast epithelial cells. International Conference on Frontiers in Cancer Prevention, Boston, MA, November 2006.

John K, Divi RL, Keshava C, Whipkey DL, Poirier M.C, Orozco CC, Shockley ME, Weston A and Nath J: Modulation by chlorophyllin of Benzo(a)pyrene (BP)-dependant CYP1 induction and DNA adduct formation in normal human mammary epithelial cells (NHMECs) and MCF-7 cells. Environmental Mutagen Society, Vancouver, B.C., Canada, September 2006.

Shockley ME, Divi RL, Keshava C, Orozco CC, Whipkey DL, Weston A, Nath J, and Poirier MC: Chlorophyllin, a chemopreventive agent, differentially modulates benzo(a)pyrene-induced gene expression and DNA damage in normal and cancer cells.  NIH Postbacc Research Festival, Bethesda, MD, May 2006.

John K, Divi RL, Shockley ME, Keshava C, Whipkey DL, Poirier MC, Weston A, and Nath, J: Chlorophyllin differentially modulates CYP1 gene expression in normal human mammary epithelial cells (NHMECs) exposed to benzopyrenes. AACR, Washington, D.C., April 2006.